흡연자의 Porphyromonas gingivalis 유전형 분포 조사
Genotype distribution of Porphyromonas gingivalis among smokers
김진경, 김지혜, 송근배, 최연희,
소속 상세정보
김진경 ( Kim Jin-Kyoung ) - Kyungpook National University School of Dentistry Department of Preventive Dentistry
김지혜 ( Kim Ji-Hye ) - Kyungpook National University School of Dentistry Department of Preventive Dentistry
송근배 ( Song Keun-Bae ) - Kyungpook National University School of Dentistry Department of Preventive Dentistry
최연희 ( Choi Youn-Hee ) - Kyungpook National University School of Dentistry Department of Preventive Dentistry
Abstract
Objectives: The purpose of this study was to determine the difference in the genotype distribution of Porphyromonas gingivalis (P. gingivalis ), the main cause of periodontal disease, according to smoking status.
Methods: Two hundred thirty adults with periodontal disease were selected as subjects and were classified into either a smoking or non-smoking group. Smoking behavior was assessed with a self-administered questionnaire, and subgingival plaque was collected and analyzed using polymerase chain reaction to confirm the P. gingivalis genotype. For statistical analysis, SPSS Ver 25.0 was used.
Results: P. gingivalis was expressed in 224 subjects (97.4%), and there was no difference in its expression rate according to smoking. However, there was a significant difference in smoking in type III genotype and smoking period in type II genotype with P. gingivalis (P =0.003).
Conclusions: Although smoking was not related to the overall distribution of P. gingivalis , increased volume and duration may inhibit the expression of type II and type III genotypes.
키워드
Genotype; Smoking; Porphyromonas gingivalis
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